GASTROPATHY DIABETIC PDF

The most commonly prescribed phenothiazine agent for DGP is prochlorperazine, a neuroleptic with a potency 10 to 20 times that of chlorpromazine. Other, less commonly used antiemetic agents include the antihistamines cyclizine and dimenhydrinate. Cyclizine is available as a tablet and also in injectable form, and dimenhydrinate is available as a tablet, liquid suspension, and suppository. The adverse effects include drowsiness, dry mouth, blurred vision, difficulty urinating, constipation, palpitations, dizziness, insomnia, and tremor. The serotonin receptor antagonists are occasionally used to treat DGP, although they are expensive and there are no data to support their use in this setting.

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Dig Dis Sci. Diabetic gastropathy: gastric neuromuscular dysfunction in diabetes mellitus: a review of symptoms, pathophysiology, and treatment. Koch KL 1. Diabetic gastropathy is a term that encompasses a number of neuromuscular dysfunctions of the stomach, including abnormalities of gastric contractility, tone, and myoelectrical activity in patients with diabetes.

These abnormalities range from tachygastrias to antral hypomotility and frank gastroparesis. Diabetic gastropathies may be acutely produced during hyperglycemia. Symptoms of chronic diabetic gastropathy include chronic nausea, vague epigastric discomfort, postprandial fullness, early satiety, and vomiting. Because these symptoms are nonspecific, other disorders such as mechanical obstruction of the gastrointestinal tract, gastroesophageal reflux disease, cholecystitis, pancreatitis, mesenteric ischemia, and drug effects should be considered.

Neuromuscular abnormalities of the stomach may be assessed noninvasively with gastric emptying tests, electrogastrography, and ultrasound. Diet and glucose control also are important in the management of diabetic gastropathy. As the pathophysiology of diabetic gastropathy is better understood, more specific and improved treatments will evolve.

CUENTOS DE FUTBOL OSVALDO SORIANO PDF

Gastroparesis

Dig Dis Sci. Diabetic gastropathy: gastric neuromuscular dysfunction in diabetes mellitus: a review of symptoms, pathophysiology, and treatment. Koch KL 1. Diabetic gastropathy is a term that encompasses a number of neuromuscular dysfunctions of the stomach, including abnormalities of gastric contractility, tone, and myoelectrical activity in patients with diabetes.

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Gastropathy 101

Differential Diagnosis When taking a patient history, clinicians should question the patient carefully about all associated gastrointestinal symptoms and ascertain the duration, severity, and precise nature of each symptom. Although diabetic gastropathy is most common in patients with long-standing insulin-dependent diabetes, it also occurs in patients who do not require insulin and in those in whom diabetes has been only recently diagnosed. It should be noted, however, that many patients with type 2 diabetes may have had the condition for many years before diagnosis. Diabetic gastropathy is frequently associated with other diabetic complications, such as retinopathy, peripheral neuropathy, and nephropathy.

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